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  "Package": "easyLSEA",
  "Title": "Lipid Set Enrichment Analysis with Dual KS and 'fgsea' Engines",
  "Version": "0.2.1",
  "Authors@R": "person(\"David\", \"Guardamino Ojeda\",\nrole = c(\"aut\", \"cre\"),\nemail = \"david.guardamino@gmail.com\",\ncomment = c(ORCID = \"0000-0002-3122-2218\"))",
  "Description": "Provides biology-aware lipid set enrichment analysis\n(LSEA) for lipidomics data using dual engines: the\nKolmogorov-Smirnov test and the fast gene set enrichment\nalgorithm from the 'fgsea' package. Annotates lipids into\nbiological groups at three levels (lipid class, LIPID MAPS\ncategory, functional category) and tests for coordinated\ndirectional shifts between conditions. Includes fatty acid\nchain analysis with trend plots weighted by lipid abundance\n(Spearman rank correlation, configurable smoothing),\nwide-format chain position output (sn-1, sn-2, sn-3, sn-4),\nannotation confidence filtering, and export utilities for\nreproducible reporting in CSV, 'Excel', and PDF formats.\nVignettes are available in English and Spanish. Methods are\nbased on Subramanian et al. (2005)\n<doi:10.1073/pnas.0506580102> and Korotkevich et al. (2021)\n<doi:10.1101/060012>.",
  "License": "MIT + file LICENSE",
  "Encoding": "UTF-8",
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  "URL": "https://github.com/DavidGO464/easyLSEA",
  "BugReports": "https://github.com/DavidGO464/easyLSEA/issues",
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  "VignetteBuilder": "knitr",
  "Language": "en-US",
  "Repository": "https://davidgo464.r-universe.dev",
  "Date/Publication": "2026-06-08 17:43:09 UTC",
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  "Packaged": {
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    "User": "root"
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  "Author": "David Guardamino Ojeda [aut, cre] (ORCID:\n<https://orcid.org/0000-0002-3122-2218>)",
  "Maintainer": "David Guardamino Ojeda <david.guardamino@gmail.com>",
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      "date": "2026-05-22"
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    "enrichment-analysis",
    "fgsea",
    "lipidomics",
    "lipids",
    "mass-spectrometry"
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      "title": "Example lipidomics dataset",
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      "class": [
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      ],
      "fields": [
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        "LipidClass",
        "logFC",
        "P.Value",
        "adj.P.Val",
        "sig"
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    {
      "page": "annotate_lipid",
      "title": "Annotate lipid names with LIPID MAPS classification",
      "topics": [
        "annotate_lipid"
      ]
    },
    {
      "page": "annotate_lipids",
      "title": "Annotate lipid names with class and category information",
      "topics": [
        "annotate_lipids"
      ]
    },
    {
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      "title": "Default chain analysis class configuration",
      "topics": [
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      ]
    },
    {
      "page": "easyLSEA",
      "title": "Lipid Set Enrichment Analysis — full pipeline",
      "topics": [
        "easyLSEA"
      ]
    },
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      "title": "Export easyLSEA results to disk",
      "topics": [
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      ]
    },
    {
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      "title": "Example lipidomics dataset",
      "topics": [
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    },
    {
      "page": "parse_lipid_chains",
      "title": "Parse acyl chain composition from a lipidomics data.frame",
      "topics": [
        "parse_lipid_chains"
      ]
    },
    {
      "page": "plot_chains",
      "title": "Generate chain analysis plots",
      "topics": [
        "plot_chains"
      ]
    },
    {
      "page": "plot_distribution",
      "title": "Distribution enrichment boxplot per lipid set",
      "topics": [
        "plot_distribution"
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    },
    {
      "page": "plot_lsea",
      "title": "Generate LSEA enrichment plots",
      "topics": [
        "plot_lsea"
      ]
    },
    {
      "page": "print.easyLSEA_result",
      "title": "Print method for easyLSEA_result",
      "topics": [
        "print.easyLSEA_result"
      ]
    },
    {
      "page": "run_lsea",
      "title": "Lipid Set Enrichment Analysis",
      "topics": [
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    },
    {
      "page": "summary.easyLSEA_result",
      "title": "Summary method for easyLSEA_result",
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